Publikationen

PUBLIKATIONEN

Fernsehdokumentation

"The Plastic Fantastic Brain", Episode 2/4" - Fernsehdokumentation über "Blindsight" - Stornoway Enterprises , Kanada 2009 - 3 GEMINI NOMINATIONS FOR "THE PLASTIC FANTASTIC BRAIN! Best Science, Technology, Nature, Environment or Adventure

>This fascinating ... programme explores cutting edge research surrounding the brain and its ability to function. ... two renowned neurologists are working to understand the brain's "plasticity" and introduce us to a woman who functions well with literally half a brain and a blind professor who learns to "see" with his tongue...<
IMDb - Zusammenfassung Film - The Plastic Fantastic Brain Episode 2/4 Beschreibung der Fernsehdokumentation "The Plastic Fantastic Brain"



Monographien

„Neuroophthalmologische Prävention“ Leh SE (2018) Handbuch neuropsychologischer Testverfahren Band 2 - Hrsg. von D. Schellig, R. Drechsler, D. Heinemann, W. Sturm, Hogrefe Verlag    


“Neuronal Substrates of Blindsight in Hemispherectomized Subjects: Behavioral and Diffusion Tensor Imaging Tractography Studies.” Leh SE (2008). VDM Verlag ISBN 3639045769.

"Investigation of the Spatial Summation Effect in normal and hemispherectomized patients. A behavioural study." Universität Hamburg, Germany: March2003 - Diplomarbeit  

"Neuronal Substrates of Blindsight in Hemispherectomized Subjects (Revealing the contribution of the superior colliculus to blindsight in hemispherectomized subjects. A behavioural and neuroimaging study.)” Doktorarbeit/PhD in Neuroscience, McGill University, Montreal, Canada: May 2008

 

Original Veröffentlichungen mit Peer-Review-Verfahren  

Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old.
van Bergen JMG, Li X, Quevenco FC, Gietl AF, Treyer V, Leh SE, Meyer R, Buck A, Kaufmann PA, Nitsch RM, van Zijl PCM, Hock C, Unschuld PG. Neurobiol Aging. 2018 Apr; 64:68-75

Brain amyloid burden and cerebrovascular disease are synergistically associated with neurometabolism in cognitively unimpaired older adults. Schreiner SJ, Kirchner T, Narkhede A, Wyss M, Van Bergen JMG, Steininger SC, Gietl A, Leh SE, Treyer V, Buck A, Pruessmann KP, Nitsch RM, Hock C, Henning A, Brickman AM, Unschuld PG. Neurobiol Aging. 2018 Mar;63:152-161

Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment.Michels L, Muthuraman M, Anwar AR, Kollias S, Leh SE, Riese F, Unschuld PG, Siniatchkin M, Gietl AF, Hock C. Front Aging Neurosci. 2017

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease. Quevenco FC, Preti MG, van Bergen JM, Hua J, Wyss M, Li X, Schreiner SJ, Steininger SC, Meyer R, Meier IB, Brickman AM, Leh SE, Gietl AF, Buck A, Nitsch RM, Pruessmann KP, van Zijl PC, Hock C, Van De Ville D, Unschuld PG. Alzheimers Res Ther. 2017 

Subcortical Shape Changes,Hippocampal Atrophy and Cortical Thinning in Future Alzheimer¹s Disease Patients Kälin AM, Park MT, Chakravarty MM, Lerch JP, Michels L, Schroeder C, Broicher SD, Kollias S, Nitsch RM, Gietl AF, Unschuld PG, Hock C, Leh SE. Front Aging Neurosci. 2017 

Microstructural Integrity of Hippocampal Subregions Is Impaired after Mild Traumatic Brain Injury. Leh SE, Schroeder C, Chen JK, Chakravarty MM, Park MT, Cheung B, Huntgeburth SC, Gosselin N, Hock C, Ptito A, Petrides M. J Neurotrauma. 2017 

Local subcortical grey matter volume changes and hippocampal white matter atrophy are associated with memory impairment in patients with Multiple Sclerosis. SD Broicher, O Geisseler, J German, T Pflugshaupt, RSC Amaral, M Linnebank, P Brugger, B Schuknecht, SE Leh. Multiple Sclerosis Journal 2016; 22, 55-56

Low episodic memory performance in cognitively normal elderly subjects is associated with increased posterior cingulate gray matter N-acetylaspartate: a 1H MRSI study at 7 Tesla. Schreiner SJ, Kirchner T, Wyss M, Van Bergen JM, Quevenco FC, Steininger SC, Griffith EY, Meier I, Michels L, Gietl AF, Leh SE, Brickman AM, Hock C, Nitsch RM, Pruessmann KP, Henning A, Unschuld PG. Neurobiol Aging. 2016 Dec;48:195-203. 

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment. van Bergen JM, Li X, Hua J, Schreiner SJ, Steininger SC, Quevenco FC, Wyss M, Gietl AF, Treyer V, Leh SE, Buck F, Nitsch RM, Pruessmann KP, van Zijl PC, Hock C, Unschuld PG. Sci Rep. 2016 Oct 17;6:35514 

Hippocampal shape alterations are associated with regional Aβ load in cognitively normal elderly individuals. Schroeder C, Park MT, Germann J, Chakravarty MM, Michels L, Kollias S, Kroll SL, Buck A, Treyer V, Savaskan E, Unschuld PG, Nitsch RM, Kälin AM, Hock C, Gietl AF, Leh SE. Eur J Neurosci. 2016 Sep 20 

Simultaneous quantitative susceptibility mappin-MRI and 18F-Flutametamol-PET indicate functional impact of cerebral iron and Amyloid-6 plaque burden in cognitively normal super-agers. van Bergen J, Quevenco FC, Leh SE, Gietl A, Treyer V, Meyer R, Nitsch R, Hock C, Unschuld P. Neurobiology of Aging 2016 (39) S9 

Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly apolipoprotein epsilon-4 carriers. Michels L, Warnock G, Buck A, Macauda G, Leh SE, Kaelin AM, Riese F, Meyer R, O’Gorman R, Hock C, Kollias S, Gietl AF. Journal of Cerebral Blood Flow & Metabolism 2016 Mar;36(3):581-95. PMID: 26661143 

Volumetric and shape analysis of the thalamus and striatum in amnestic mild cognitive impairment. Leh SE, Kälin AM, Schroeder C, Park MT, Chakravarty MM, Freund P, Gietl AF, Riese F, Kollias S, Hock C, Michels L. J Alzheimers Dis. 2015;49(1):237-49. PMID: 26444755 2015: 

Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner. Gietl AF, Warnock G, Riese F, Kälin AM, Saake A, Gruber E, Leh SE, Unschuld PG, Kuhn FP, Burger C, Mu L, Seifert B, Nitsch RM, Schibli R, Ametamey SM, Buck A, Hock C Neurobiol Aging. 2015 Apr;36(4):1619-28. PMID: 25702957 

Posterior cingulate γ-aminobutyric acid and glutamate/glutamine are reduced in amnestic mild cognitive impairment and are unrelated to amyloid deposition and apolipoprotein E genotype. Riese F, Gietl A, Zölch N, Henning A, O’Gorman R, Kälin AM, Leh SE, Buck A, Warnock G, Edden RAE, Luechinger R, Hock C, Kollias S, Michels L Neurobiol Aging. 2015 Jan;36(1):53-9. PMID: 25169676 2014: 

Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System. Steininger SC, Liu X, Gietl A, Wyss M, Schreiner S, Gruber E, Treyer V, Kälin A, Leh SE, Buck A, Nitsch RM, Prüssmann KP, Hock C, Unschuld PG (2014). Front Aging Neurosci. 2014 Mar 18;6:52 PMID: 24672483 

Posterior cingulate GABA and GLX are reduced in amnestic mild cognitive impairment. Riese F, Gietl A, Zölch N, Henning A, O’Gorman R, Kälin AM, Leh SE, Buck A, Warnock G, Luechinger R, Hock C, Kollias S, Michels L. Alzheimer`s & Dementia July 2014 Volume 10, Issue 4, Supplement, Page P713 

Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System. Steininger SC, Liu X, Gietl A, Wyss M, Schreiner S, Gruber E, Treyer V, Kälin A, Leh S, Buck A, Nitsch RM, Prüssmann KP, Hock C, Unschuld PG. Front Aging Neurosci. 2014 Mar 18;6:52. PMID: 24672483 

Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects. Schreiner SJ, Liu X, Gietl AF, Wyss M, Steininger SC, Gruber E, Treyer V, Meier IB, Kälin AM, Leh SE, Buck A, Nitsch RM, Pruessmann KP, Hock C, Unschuld PG. Front Aging Neurosci. 2014 Sep 9;6:240. PMID: 25249977 2013 

Probing 7 Tesla High Field Strength Magnetic Resonance Imaging (MRI) as Potential Biomarker for Beta-Amyloid Associated Neuronal Stress Paul G Unschuld, Anton Gietl, Thomas Kirchner, Michael Wyss, Alfred Buck, Sandra Leh-Seal, Roger M Nitsch, Anke Henning, Klaas Pruessmann, Christoph Hock BIOLOGICAL PSYCHIATRY 2013 (73)9: 82S 2011/2012 

Superior colliculi involvement in poststroke unilateral spatial neglect: A pilot study. Ogourtsova T, Korner-Bitensky N, Leh SE, Eskes G, Ptito A. Topics in stroke rehabilitation 18 (6), 770-785 2010 

The neural circuitry of executive functions in healthy subjects and Parkinson's disease. Leh SE, Petrides M, Strafella AP. Neuropsychopharmacology. 2010 Jan;35(1):70-85 2008 

Blindsight mediated by an S-cone-independent collicular pathway: an fMRI study in hemispherectomized subjects.Leh SE, Ptito A, Schönwiesner M, Chakravarty MM, Mullen KT. J Cogn Neurosci. 2010 Apr;22(4):670-82. 

Right impairment of temporal order judgements in dyslexic children. Pérez A, García L, Lage A, Leh SE, Valdés-Sosa M. Laterality. 2008 Nov;13(6):545-60 

The connectivity of the human pulvinar: a diffusion tensor imaging tractography study. Leh SE, Chakravarty MM, Ptito A. Int J Biomed Imaging. 2008;2008:789539. 2007 

Fronto-striatal connections in the human brain: a probabilistic diffusion tractography study. Leh SE, Ptito A, Chakravarty MM, Strafella AP. Neurosci Lett. 2007 May 29;419(2):113-8. 2006 

Absence of S-cone input in human blindsight following hemispherectomy. Leh SE, Mullen KT, Ptito A. Eur J Neurosci. 2006 Nov;24(10):2954-60. 23. 

Unconscious vision: new insights into the neuronal correlate of blindsight using diffusion tractography. Leh SE, Johansen-Berg H, Ptito A. Brain. 2006 Jul;129(Pt 7):1822-32.


Übersichtsarbeiten (Reviews)

Neural substrates of blindsight after hemispherectomy. Ptito A, Leh SE. Neuroscientist 2007 Oct;13(5):506-18.

The neural circuitry of executive functions in healthy subjects and Parkinson's disease. Leh SE, Petrides M, Strafella AP Neuropsychopharmacology 2010 35(1):70-85.


Populärwissenschaftliche Veröffentlichungen und Publizistik

Zeitungsbericht über meine Forschung und Arbeit  “Das Echo-Die Zeitung für Deutschsprachige in Kanada und USA! ”, Montreal, Kanada

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